Xeomin Overview

Xeomin (incobotulinumtoxinA) is the latest in the clinical line of injectable neuromodulators indicated for the non-surgical management of frown lines. Similar to Botox Cosmetic and Dysport, Xeomin is a prescription medicine made of purified protein derived from Clostridium Botulinum.

Dr. Vallecillos - Xeomin

Procedure Walk-Through

  1. Preparation

    Prior to undergoing a Xeomin treatment, you should discuss any medications or known allergies with Dr. Vallecillos. Any underlying neurological history should also be discussed with Dr. Vallecillos in order to avoid potential complications. Medications to be avoided include those that contain aspirin, Motrin, or Advil, for a period of two weeks prior to your appointment. On the day of the procedure, your face should be free of any makeup or lotion.

  2. Anesthesia

    Anesthetic options prior to undergoing Xeomin treatments include a topical numbing cream to the affected area to minimize a patient’s discomfort during the procedure. However, most patients require no pre-procedural anesthesia for Xeomin treatment.

  3. Xeomin injections will be administered using a very fine needle to the areas of the face that require treatment, usually for moderate to severe frown lines between the eyebrows and other facial wrinkles.

Xeomin FAQ

Who is a candidate for Xeomin?

You should consider Xeomin if you are an adult between the ages of 25 and 65 and suffer from moderate to severe facial lines and wrinkles, especially those found in between the eyes, across the forehead, and the crows feet area. Additionally, if you symptoms of severe sweating or hyperhydrosis- including the armpits and palms of hands – Xeomin may be a viable treatment option for you.

What is the recovery time for Xeomin?

Patients should experience little to no recovery time after a Xeomin treatment, although it is recommended that patients refrain from exercise for a period of 24 hours following treatment. No dressings are required, and any swelling that may appear at the injection site usually disappear within 30 minutes.

Are there risks or side effects with Xeomin?

The most common side effect of Xeomin is tenderness and bruising at the injection sites, usually slight and temporary. Applying ice to the affected areas directly after the procedure can help to minimize these risks. Though unusual, some patients experience temporary headaches. This typically resolves within one week. Other rare complications can include heaviness of the brow region, and blepharoptosis (or drooping of the upper eyelid). You should not use Xeomin if you have a skin infection in the regional area, as it can exacerbate the condition. Additionally, if you have a history of a neurological disorder such as Eaton-Lambert Syndrome, ALS, or Myasthenia Gravis, this should be discussed with Dr. Vallecillos as special consideration is necessary prior to treatment with a neurotoxin.

How long do the results last?

Results from Xeomin injections will begin to show within 2-14 days after the procedure, and should last for up to 3-5 months. While additional injections of Xeomin may be necessary for optimal results, injection schedules are typically 90-120 days apart on average.

How does Xeomin differ from Botox Cosmetic and Dysport?

While Xeomin has basic molecular similarities with its contemporaries, Botox Cosmetic and Dysport, all of which are botulinum toxin type A, there are notable differences worth mentioning that have clinical implications. Unlike Botox Cosmetic and Dysport, Xeomin requires no refrigeration during storage in its freeze-dried state. This has clear advantages in terms of its storage and distribution.

Dr. Vallecillos - Botox and Xeomin

Additionally, the principal molecule of Xeomin is “naked” meaning that it has no additives. What does this mean for the patient? The lack of additives in Xeomin lessens its chances of causing an immune response by the body, which could theoretically lead to early immunity and loss of efficacy by the product, a significant advantage over both Botox Cosmetic and Dysport.

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Dr. Vallecillos - American Board of Plastic Surgery
Dr. Vallecillos - Top Rated Board Certified Plastic Surgeon
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Dr. Vallecillos - University of California Los Angeles

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