LAVIV (azficel-T) is a new, autologous cellular treatment to reduce the appearance of deep nasolabial lines. LAVIV uses a sample of your own skin cells to produce a purified mixture of fibroblasts (the collagen-producing components of your skin). Your personal mixture is then returned to your surgeon’s office, where it will be injected into the affected areas during a three-part treatment. The fibroblasts encourage firmness and structure in the skin, eventually reducing the appearance of deep wrinkles.
The first step in LAVIV cellular therapy is to make an appointment with your surgeon for the collection of a skin sample. The sample is sent to LAVIV’s manufacturing facility, where your own fibroblasts are purified and multiplied. Your personalized mixture is then returned to your surgeon’s office, usually within three months.Before beginning treatment, be sure to discuss any allergies you may have, disclose any medications you may be taking, and discuss any history of keloids, scarring, skin cancer, or other skin disorders with your surgeon.
Once your personalized LAVIV has been delivered to your surgeon’s office, you can begin the treatment series.
- During a single session, a small needle is used to inject the mixture into the affected areas. It is important to note that LAVIV’s efficacy has only been tested on nasolabial lines (those running from the outside of the nose to the corner of the mouth).
- Botox Cosmetic and Dysport may be used in conjunction with LAVIV to further reduce lines or address wrinkles in other areas of the face, such as the forehead.Dermal fillers like Radiesse and Juvederm may also be used to add facial fullness, soften lines, and plump lips.
Who is a candidate for LAVIV?
You should consider LAVIV if you suffer from moderate to severe nasolabial fold wrinkles (the lines that run from the outside of the nose to the corners of the mouth).
Be sure to discuss any allergies you may have with your surgeon, including allergies to the following:
- Antibiotics gentamicin or amphotericin
- Dimethyl sulfoxide (DMSO)
- Any bovine-based products
What is the recovery time for LAVIV?
There is usually no patient downtime associated with LAVIV. Some patients experience redness, bruising, or other temporary side effects near the injection sites, but in most cases these resolve on their own within one week.
Are there risks or side effects with LAVIV?
You should expect some temporary redness, bruising, swelling, pain, bleeding, lumps, irritation, and itchiness near the injection sites.
Since LAVIV is created from the patient’s own cells, it is a very safe procedure with very little risk. However, using another patient’s cells can cause a serious immune reaction. Make sure that the vial has your correct information on it before it is administered.
Do not use LAVIV if you have a skin infection, as it can cause the condition to worsen.
How long do the results last?
Most patients will need to receive three separate treatments spaced apart 3-6 weeks to see optimal results. Follow-up treatments may be necessary to maintain results beyond six months.